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It is involved in the viral attachment and in the host cell entry: the S1 subunit is able to bind the angiotensin-converting enzyme 2 (ACE2) receptor while, in a second step, the S2 subunit allows the virus to enter the cell by membrane fusion (122)

The reduced food intake can make this dip more noticeable initially

doi: 10.1016/j.trecan.2021.04.003 212 SuzukiSTanakaTPoyurovskyMVNaganoHMayamaTOhkuboSet al

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Nutritional deficienciesparticularly in B vitamins, magnesium, and amino acidsdevelop during intensive weight loss and independently trigger depression